Chapter 2: Dragon Brood

After defeating Mistress Yudai, Hyakkimaru and Dororo come across a ronin  named Tanosuke in a desert-like area. This ronin wields a sword known as Dragon Brood, which is possessed by one of The 48 Fiends that had stolen Hyakkimaru's body parts. After Hyakkimaru defeats the masterless samurai, he flees. Dororo follows him and steals his sword. Dragon Brood tells Dororo to kill to satisfy its thirst for blood, which causes Dororo to attack Tanosuke's sister Misaki. However, Hyakkimaru arrives in time to take the sword out of Dororo's hands. Tanosuke reclaims the sword and fights Hyakkimaru, but sacrifices himself to Dragon Brood after being defeated again. Hyakkimaru destroys the blade and regains his spine.

Fiends

 * Giant Fire Wheel
 * Dragon Brood
 * Impaler
 * Night Terror
 * Nameless Fiend
 * Draconus
 * Fiend Misaki